Weight Loss Medications
Our goal for injections are: LOW dosing, LOW side effects with HIGH results
Retatrutide
(Triple Agonist: GLP-1, GIP, Glucagon)
Why Choose Retatrutide:
- Best for: Patients seeking maximum weight loss potential and metabolic improvement beyond just appetite control in a much shorter time frame than the others.
- How It Works: Retatrutide activates three receptors (GLP-1, GIP, and glucagon) that regulate appetite, fat metabolism, and insulin sensitivity.
Pros:
- Early studies show greater weight loss than Semaglutide or Tirzepatide with less muscle loss
- Potential additional benefits for everything tirzepatide offers plus fatty liver, heart health, and muscle metabolism.
Cons:
- Still in clinical trials, meaning limited availability and higher cost when released.
- May have more side effects due to multi-receptor activation but generally increased risk with the increased dose.
Tirzepatide
(Dual Agonist: GLP-1 & GIP)
Why Choose Tirzepatide:
- Best for: Patients looking for faster weight loss with added metabolic benefits, including improvements in blood sugar and insulin sensitivity.
- How It Works: Tirzepatide combines GLP-1 (appetite control) with GIP (metabolic regulation), offering superior weight loss and improved glycemic control compared to GLP-1 alone.
Pros:
- Faster weight loss and greater reductions in body fat compared to Semaglutide.
- Additional benefits for insulin resistance, fatty liver, smoking/drinking cessation, sleep apnea, bone health, decreasing inflammation and improved cardiovascular health.
Cons:
- More expensive than Semaglutide.
- Slightly higher risk of gastrointestinal side effects at the higher doses but is often specific to food choices.
Semaglutide
(GLP-1 Agonist)
Why Choose Semaglutide:
- Best for: Patients who want a proven, cost-effective solution for long-term weight loss with solid clinical data.
- How It Works: Semaglutide mimics GLP-1, a hormone that helps regulate appetite and promote satiety.
Pros:
- Most studied and widely available medication with a long track record of safety and efficacy.
- Slightly lower cost compared to Tirzepatide.
Cons:
- May result in slower weight loss than Tirzepatide or Retatrutide.
- More gastrointestinal side effects at higher doses and typically requires higher doses for weight loss but getting to the higher doses can be slow due to SE potential.
How to Choose the Right Option for You
- Looking for the most weight loss possible which can be attainable in a shorter time with less muscle loss potential?
- Retatrutide may be worth waiting for if you’re looking for maximum fat loss with added metabolic benefits.
- Want faster results with broader metabolic health improvements?
- Tirzepatide is a great option if you’re looking for more than just weight loss, especially if you have insulin resistance or prediabetes.
- Prefer a proven, affordable solution?
- Semaglutide offers solid, consistent weight loss results with lower costs and more availability.
Final Thoughts
Each medication offers unique advantages, and the right choice depends on your personal health profile, goals, and budget. Our providers are here to help guide you through the process and recommend the safest, most effective option tailored to your needs.
Ready to get started? Book an appointment today!
Additional Weight Loss Medications and Peptides
In addition to Retatrutide, Tirzepatide and Semaglutide , we offer several other options for patients seeking weight loss and metabolic health solutions. These include but are not limited to:
Tesamorelin
Tesamorelin is a growth hormone-releasing hormone (GHRH) analog used to reduce visceral fat and improve body composition. It is FDA-approved for HIV-associated lipodystrophy but is also used off-label for general weight loss and metabolic enhancement.
- How It Works: Stimulates the pituitary gland to release growth hormone, which aids in fat loss and muscle preservation.
- Pros:
- Effective for targeting stubborn visceral fat
- Can improve insulin sensitivity and cardiovascular health
- Cons:
- Requires daily injections
- May cause fluid retention or mild joint pain
AOD 9604
AOD 9604 is a peptide fragment derived from human growth hormone (HGH) that targets fat metabolism without affecting blood sugar levels.
- How It Works: It stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat storage), making it an effective adjunct for weight loss.
- Pros:
- Non-hormonal, minimal side effects
- Can aid in fat loss while preserving lean muscle
- Cons:
- Best used in conjunction with lifestyle modifications for optimal results
Tesofensine
Tesofensine is an oral weight loss medication originally developed as a treatment for neurodegenerative diseases. It acts as a triple reuptake inhibitor, affecting dopamine, serotonin, and norepinephrine levels to reduce appetite and increase energy expenditure.
- Pros:
- Powerful appetite suppression and metabolic boost
- Can enhance mood and energy levels
- Cons:
- Potential for side effects like insomnia, dry mouth, and increased heart rate
Calgrilinotide
Calgrilinotide is a peptide currently under investigation for its ability to reduce appetite by antagonizing the calcitonin receptor. It may serve as an adjunct to GLP-1 receptor agonists for enhanced weight loss.
- Pros:
- Can provide additional appetite suppression when used with other peptides
- May enhance long-term weight management
- Cons:
- Not yet widely available
Phentermine
Phentermine is a well-established FDA-approved prescription medication for short-term weight loss. It works by suppressing appetite and increasing energy levels.
- Pros:
- Effective for quick appetite suppression
- Can provide a significant boost to early weight loss efforts
- Cons:
- Potential for side effects like increased heart rate, insomnia, and dry mouth
- Not recommended for long-term use
Contrave (Naltrexone SR/Bupropion SR)
Contrave is an FDA-approved combination medication for weight loss that works by affecting the brain’s reward system and appetite control.
- How It Works: Combines bupropion, which suppresses appetite, and naltrexone, which reduces food cravings by modulating dopamine response.
- Pros:
- Can reduce emotional eating and food cravings
- Helps regulate appetite and satiety
- Cons:
- Can cause nausea, headache, and dizziness in some patients
- Requires monitoring due to potential interaction with other medications
Mazdutide (Coming Soon)
Mazdutide is a dual GLP-1 and glucagon receptor agonist being developed to enhance fat loss, improve metabolic health, and offer additional benefits beyond existing GLP-1 medications.
- Potential Benefits:
- Increased fat burning through glucagon receptor activation
- Enhanced weight loss potential with possible cardiovascular benefits
- Status: Currently in late-stage clinical trials with promising results
Survutide (Coming Soon)
Survutide is an experimental peptide targeting satiety regulation and fat metabolism. It has shown promise in preclinical studies for inducing significant fat loss without affecting lean muscle mass.
- Potential Benefits:
- Enhanced appetite suppression
- Improved metabolic regulation
- Status: Early-stage clinical trials
SLU-PP-332 (coming soon)
A novel research peptide, SLU-PP-332, shows promise in promoting weight loss by regulating appetite and improving metabolic efficiency.
- How It Works: It targets specific brain pathways involved in hunger signaling and fat metabolism.
- Pros:
- Potential for long-term weight loss maintenance
- Minimal known side effects in early studies
- Cons:
- Still undergoing clinical trials; limited availability
- Some call this “exercise in a shot”